Impact on the quality of life of the treatment of adductor spasmodic dysphonia with botulinum toxin A

Impacto en la calidad de vida del tratamiento de disfonía espasmódica aductora con toxina botulínica A

Published 2021-12-18

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Vol. 3 No. 2 (2021)
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Research Article
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Impact on the quality of life of the treatment of adductor spasmodic dysphonia with botulinum toxin A. Rev. Investig. Innov. Cienc. Salud [Internet]. 2021 Dec. 18 [cited 2024 Dec. 21];3(2):24-3. Available from: https://riics.info/index.php/RCMC/article/view/66
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https://doi.org/10.46634/riics.66
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Carolina Oliva Guerrero
Hospital Clínico Universidad de Chile; Santiago; Chile.
    https://orcid.org/0000-0003-2202-1948
    Luis Barahona Acevedo
    Hospital Clínico Universidad de Chile; Santiago; Chile.
      https://orcid.org/0000-0003-4293-9000
      Javiera Castro Arenas
      Universidad de Chile; Santiago; Chile.
        https://orcid.org/0000-0001-9792-1751
        Christian Olavarría Leiva
        Hospital Clínico Universidad de Chile; Santiago; Chile.
          https://orcid.org/0000-0001-8520-0164
          Show authors biography

          Introduction. Laryngeal dystonia or spasmodic dysphonia is characterized by involuntary contractions of internal laryngeal muscles that are triggered when speaking, being the adductor form the most frequent. Botulinum toxin injection is the management of choice. There are several validated instruments to assess response to therapy, one of them is the Voice Handicap Index-10 (VHI-10) questionnaire. The objective of this study is to characterize patients with adductor spasmodic dysphonia and evaluate the impact of the toxin on their quality of life.

          Method. A descriptive retrospective study was carried out in adult patients with a diagnosis of adductor spasmodic dysphonia treated with botulinum toxin A, between 2013-2021 at the Hospital Clínico Universidad de Chile. The epidemiological data of the patients and the VHI-10 survey were obtained before and after one month of each toxin injection was requested.

          Results. 55 patients (218 procedures) were included. The average dose used was 9.18 IU with an average interval of 7.4 months. The average VHI-10 score in the initial evaluation was 29.4 and post-infiltration was 14.96, being this difference significant (p <0.000001). In our series, almost a third had an associated neurological pathology, and 3.67% of mild and transitory complications were reported.

          Conclusion. Adductor spasmodic dysphonia has a great impact on the quality of life of patients, which is significantly reduced by injecting botulinum toxin A, a procedure that has been shown to be safe and effective.

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