Impact of Computerized Neuropsychological Rehabilitation in a Patient with Sickle Cell Anemia and ADHD. Single-case Experimental Study

Impacto de la rehabilitación neuropsicológica computarizada en un paciente con anemia de células falciformes y TDAH. Estudio experimental de caso único

Published 2023-06-16 — Updated on 2023-07-13

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Vol. 5 No. 1 (2023)
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Research Article
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Impact of Computerized Neuropsychological Rehabilitation in a Patient with Sickle Cell Anemia and ADHD. Single-case Experimental Study. Rev. Investig. Innov. Cienc. Salud [Internet]. 2023 Jul. 13 [cited 2024 Nov. 24];5(1):177-90. Available from: https://riics.info/index.php/RCMC/article/view/186
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https://doi.org/10.46634/riics.186
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Juan Pablo Pérez Pereira
Departamento de Pediatría y Puericultura; Facultad de Medicina; Universidad de Antioquia; Medellín; Colombia. / Universidad CES; Medellín; Colombia.
    https://orcid.org/0000-0002-9916-4739
    Jorge Mauricio Cuartas Arias
    Departamento de Psicología; Escuela de Humanidades; Universidad EAFIT; Medellín; Colombia.
      https://orcid.org/0000-0001-9007-713X
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      Introduction. Sickle cell anemia (SCA) is a genetic disease that causes a malformation in red blood cells, making them more fragile and leading to their lysis. Due to their abnormal shape, they predispose to occlusive events in smaller blood vessels, including those in the central nervous system. Literature documents the presence of silent and non-silent cerebral infarctions associated with SCA, along with respective cognitive impairments. In recent years, cognitive impairment and a higher prevalence of neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD) have been reported in children with SCA who have not experienced ischemic brain events.

      Method. An experimental and prospective single-case study was conducted, consisting of a rehabilitation program using the CogniFit platform for cognitive training in attention and concentration. Measurements of attention and inhibitory control responses were taken during 45 sessions, using the Cognitive Assessment Battery for Attention (CAB-AT).

      Results. It was observed that the intervention had a significant impact on the attention component, which remained above the baseline even after discontinuing the intervention. However, no significant impact was found on inhibitory control.

      Conclusion. Although the intervention improved attention, it did not have the same effect on inhibitory control. Complementing rehabilitation with pharmacological management and designing new studies involving heterogeneous populations are recommended.

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